Liranol
Brand names,
Liranol
Analogs
Liranol
Brand Names Mixture
Liranol
Chemical_Formula
C17H20N2S
Liranol
RX_link
No information avaliable
Liranol
fda sheet
Liranol
msds (material safety sheet)
Liranol
Synthesis Reference
No information avaliable
Liranol
Molecular Weight
284.42 g/mol
Liranol
Melting Point
< 25 oC
Liranol
H2O Solubility
14.2 mg/L
Liranol
State
Liquid
Liranol
LogP
4.893
Liranol
Dosage Forms
Tablet; Oral liquid; Injection
Liranol
Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Liranol
Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Liranol
Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Liranol
side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Liranol
Patient Information
No information avaliable
Liranol
Organisms Affected
Humans and other mammals