Prazine
Prazine Brand names, Prazine Analogs
- AB
- Aminazin
- Aminazine
- Ampazine
- Ampliactil
- Amplictil
- Berophen
- CPZ
- Chlor-Promanyl
- Chlordelazin
- Chlorderazin
- Chlorpromados
- Chlorpromazine Hcl
- Chlorpromazine Hcl Intensol
- Chlropromados
- Contomin
- Elmarin
- Esmind
- Esparin
- Fenactil
- Fenaktyl
- Fraction
- Largactil
- Largactilothiazine
- Largactyl
- Liranol
- Megaphen
- Neo-Hibernex
- Novomazina
- Phenactyl
- Phenothiazine
- Prazin
- Prazine
- Proma
- Promactil
- Promapar
- Promazil
- Promazin
- Promazina
- Promazine Hcl
- Promwill
- Propaphenin
- Protactyl
- Prozil
- Psychozine
- Romtiazin
- Sanopron
- Sinophenin
- Sonazine
- Sparine
- Thorazine
- Tomil
- Torazina
- Verophen
- Vesprin
- Wintermin
Prazine Brand Names Mixture
- No information avaliable
Prazine Chemical_Formula
C17H20N2S
Prazine RX_link
No information avaliable
Prazine fda sheet
Prazine msds (material safety sheet)
Prazine Synthesis Reference
No information avaliable
Prazine Molecular Weight
284.42 g/mol
Prazine Melting Point
< 25 oC
Prazine H2O Solubility
14.2 mg/L
Prazine State
Liquid
Prazine LogP
4.893
Prazine Dosage Forms
Tablet; Oral liquid; Injection
Prazine Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Prazine Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Prazine Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Prazine side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Prazine Patient Information
No information avaliable
Prazine Organisms Affected
Humans and other mammals
