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Propaphenin Brand names, Propaphenin Analogs

Propaphenin Brand Names Mixture

  • No information avaliable

Propaphenin Chemical_Formula


Propaphenin RX_link

No information avaliable

Propaphenin fda sheet

Propaphenin msds (material safety sheet)

Propaphenin Synthesis Reference

No information avaliable

Propaphenin Molecular Weight

284.42 g/mol

Propaphenin Melting Point

< 25 oC

Propaphenin H2O Solubility

14.2 mg/L

Propaphenin State


Propaphenin LogP


Propaphenin Dosage Forms

Tablet; Oral liquid; Injection

Propaphenin Indication

Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.

Propaphenin Pharmacology

Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.

Propaphenin Absorption

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

Propaphenin side effects and Toxicity

Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.

Propaphenin Patient Information

No information avaliable

Propaphenin Organisms Affected

Humans and other mammals