Promactil
Promactil Brand names, Promactil Analogs
- AB
- Aminazin
- Aminazine
- Ampazine
- Ampliactil
- Amplictil
- Berophen
- CPZ
- Chlor-Promanyl
- Chlordelazin
- Chlorderazin
- Chlorpromados
- Chlorpromazine Hcl
- Chlorpromazine Hcl Intensol
- Chlropromados
- Contomin
- Elmarin
- Esmind
- Esparin
- Fenactil
- Fenaktyl
- Fraction
- Largactil
- Largactilothiazine
- Largactyl
- Liranol
- Megaphen
- Neo-Hibernex
- Novomazina
- Phenactyl
- Phenothiazine
- Prazin
- Prazine
- Proma
- Promactil
- Promapar
- Promazil
- Promazin
- Promazina
- Promazine Hcl
- Promwill
- Propaphenin
- Protactyl
- Prozil
- Psychozine
- Romtiazin
- Sanopron
- Sinophenin
- Sonazine
- Sparine
- Thorazine
- Tomil
- Torazina
- Verophen
- Vesprin
- Wintermin
Promactil Brand Names Mixture
- No information avaliable
Promactil Chemical_Formula
C17H20N2S
Promactil RX_link
No information avaliable
Promactil fda sheet
Promactil msds (material safety sheet)
Promactil Synthesis Reference
No information avaliable
Promactil Molecular Weight
284.42 g/mol
Promactil Melting Point
< 25 oC
Promactil H2O Solubility
14.2 mg/L
Promactil State
Liquid
Promactil LogP
4.893
Promactil Dosage Forms
Tablet; Oral liquid; Injection
Promactil Indication
Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.
Promactil Pharmacology
Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.
Promactil Absorption
Absorption may be erratic and peak plasma concentrations show large interindividual differences.
Promactil side effects and Toxicity
Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.
Promactil Patient Information
No information avaliable
Promactil Organisms Affected
Humans and other mammals
