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CPZ Brand names, CPZ Analogs

CPZ Brand Names Mixture

  • No information avaliable

CPZ Chemical_Formula


CPZ RX_link

No information avaliable

CPZ fda sheet

CPZ msds (material safety sheet)

CPZ Synthesis Reference

No information avaliable

CPZ Molecular Weight

284.42 g/mol

CPZ Melting Point

< 25 oC

CPZ H2O Solubility

14.2 mg/L

CPZ State




CPZ Dosage Forms

Tablet; Oral liquid; Injection

CPZ Indication

Used as an adjunct for short term treatment of moderate and severe psychomotor agitation. Also used to treat agitation or restlessness in the elderly.

CPZ Pharmacology

Promazine belongs to a group of medications known as the phenothiazine antipsychotics. It acts by blocking a variety of receptors in the brain, particularly dopamine receptors. Dopamine is involved in transmitting signals between brain cells. When there is an excess amount of dopamine in the brain it causes over-stimulation of dopamine receptors. These receptors normally act to modify behaviour and over-stimulation may result in psychotic illness. Promazine hydrochloride blocks these receptors and stops them becoming over-stimulated, thereby helping to control psychotic illness. Promazine has weak extrapyramidal and autonomic side effects which lead to its use in the elderly, for restless or psychotic patients. Its anti-psychotic effect is also weaker and it is not useful in general psychiatry.

CPZ Absorption

Absorption may be erratic and peak plasma concentrations show large interindividual differences.

CPZ side effects and Toxicity

Side effects include: extrapyramidal symptoms, drowsiness, weight gain, dry mouth, constipation, endocrine effects (such as gynaecomastia and menstrual disturbance), sensitivity to sunlight and haemolytic anaemia.

CPZ Patient Information

No information avaliable

CPZ Organisms Affected

Humans and other mammals