Levorphanol

Levorphanol Brand names, Levorphanol Analogs

Levorphanol Brand Names Mixture

No information avaliable

Levorphanol Chemical_Formula

C₁₇H₂₃NO

Levorphanol RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Levorphanol fda sheet

Levorphanol msds (material safety sheet)

Levorphanol MSDS

Levorphanol Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Levorphanol Molecular Weight

257.371 g/mol

Levorphanol Melting Point

198-199 ^oC

Levorphanol H₂O Solubility

1840 mg/L

Levorphanol State

Solid

Levorphanol LogP

3.986

Levorphanol Dosage Forms

Tablet

Levorphanol Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Levorphanol Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Levorphanol Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Levorphanol side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Levorphanol Patient Information

No information avaliable

Levorphanol Organisms Affected

Humans and other mammals