Lemoran
Brand names,
Lemoran
Analogs
Lemoran
Brand Names Mixture
Lemoran
Chemical_Formula
C17H23NO
Lemoran
RX_link
http://www.rxlist.com/cgi/generic2/levorphanol.htm
Lemoran
fda sheet
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msds (material safety sheet)
Lemoran
Synthesis Reference
Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.
Lemoran
Molecular Weight
257.371 g/mol
Lemoran
Melting Point
198-199 oC
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H2O Solubility
1840 mg/L
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State
Solid
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LogP
3.986
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Dosage Forms
Tablet
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Indication
For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate
Lemoran
Pharmacology
Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.
Lemoran
Absorption
Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.
Lemoran
side effects and Toxicity
LD50=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.
Lemoran
Patient Information
No information avaliable
Lemoran
Organisms Affected
Humans and other mammals