Levorphan

Levorphan Brand names, Levorphan Analogs

Levorphan Brand Names Mixture

No information avaliable

Levorphan Chemical_Formula

C₁₇H₂₃NO

Levorphan RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Levorphan fda sheet

Levorphan msds (material safety sheet)

Levorphan MSDS

Levorphan Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Levorphan Molecular Weight

257.371 g/mol

Levorphan Melting Point

198-199 ^oC

Levorphan H₂O Solubility

1840 mg/L

Levorphan State

Solid

Levorphan LogP

3.986

Levorphan Dosage Forms

Tablet

Levorphan Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Levorphan Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Levorphan Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Levorphan side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Levorphan Patient Information

No information avaliable

Levorphan Organisms Affected

Humans and other mammals