Levorphanal

Levorphanal Brand names, Levorphanal Analogs

Levorphanal Brand Names Mixture

No information avaliable

Levorphanal Chemical_Formula

C₁₇H₂₃NO

Levorphanal RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Levorphanal fda sheet

Levorphanal msds (material safety sheet)

Levorphanal MSDS

Levorphanal Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Levorphanal Molecular Weight

257.371 g/mol

Levorphanal Melting Point

198-199 ^oC

Levorphanal H₂O Solubility

1840 mg/L

Levorphanal State

Solid

Levorphanal LogP

3.986

Levorphanal Dosage Forms

Tablet

Levorphanal Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Levorphanal Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Levorphanal Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Levorphanal side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Levorphanal Patient Information

No information avaliable

Levorphanal Organisms Affected

Humans and other mammals