Levorphanol Tartrate
Brand names,
Levorphanol Tartrate
Analogs
Levorphanol Tartrate
Brand Names Mixture
Levorphanol Tartrate
Chemical_Formula
C17H23NO
Levorphanol Tartrate
RX_link
http://www.rxlist.com/cgi/generic2/levorphanol.htm
Levorphanol Tartrate
fda sheet
Levorphanol Tartrate
msds (material safety sheet)
Levorphanol Tartrate
Synthesis Reference
Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.
Levorphanol Tartrate
Molecular Weight
257.371 g/mol
Levorphanol Tartrate
Melting Point
198-199 oC
Levorphanol Tartrate
H2O Solubility
1840 mg/L
Levorphanol Tartrate
State
Solid
Levorphanol Tartrate
LogP
3.986
Levorphanol Tartrate
Dosage Forms
Tablet
Levorphanol Tartrate
Indication
For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate
Levorphanol Tartrate
Pharmacology
Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.
Levorphanol Tartrate
Absorption
Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.
Levorphanol Tartrate
side effects and Toxicity
LD50=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.
Levorphanol Tartrate
Patient Information
No information avaliable
Levorphanol Tartrate
Organisms Affected
Humans and other mammals