Levorfanolo [Dcit]

Levorfanolo [Dcit] Brand names, Levorfanolo [Dcit] Analogs

Levorfanolo [Dcit] Brand Names Mixture

No information avaliable

Levorfanolo [Dcit] Chemical_Formula

C₁₇H₂₃NO

Levorfanolo [Dcit] RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Levorfanolo [Dcit] fda sheet

Levorfanolo [Dcit] msds (material safety sheet)

Levorfanolo_[Dcit] MSDS

Levorfanolo [Dcit] Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Levorfanolo [Dcit] Molecular Weight

257.371 g/mol

Levorfanolo [Dcit] Melting Point

198-199 ^oC

Levorfanolo [Dcit] H₂O Solubility

1840 mg/L

Levorfanolo [Dcit] State

Solid

Levorfanolo [Dcit] LogP

3.986

Levorfanolo [Dcit] Dosage Forms

Tablet

Levorfanolo [Dcit] Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Levorfanolo [Dcit] Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Levorfanolo [Dcit] Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Levorfanolo [Dcit] side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Levorfanolo [Dcit] Patient Information

No information avaliable

Levorfanolo [Dcit] Organisms Affected

Humans and other mammals