Levorphanolum [Inn-Latin]

Levorphanolum [Inn-Latin] Brand names, Levorphanolum [Inn-Latin] Analogs

Levorphanolum [Inn-Latin] Brand Names Mixture

No information avaliable

Levorphanolum [Inn-Latin] Chemical_Formula

C₁₇H₂₃NO

Levorphanolum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic2/levorphanol.htm

Levorphanolum [Inn-Latin] fda sheet

Levorphanolum [Inn-Latin] msds (material safety sheet)

Levorphanolum_[Inn-Latin] MSDS

Levorphanolum [Inn-Latin] Synthesis Reference

Woods LA, et al. J Pharmacol Exp Ther. 1958 Sep;124(1):1-8.

Levorphanolum [Inn-Latin] Molecular Weight

257.371 g/mol

Levorphanolum [Inn-Latin] Melting Point

198-199 ^oC

Levorphanolum [Inn-Latin] H₂O Solubility

1840 mg/L

Levorphanolum [Inn-Latin] State

Solid

Levorphanolum [Inn-Latin] LogP

3.986

Levorphanolum [Inn-Latin] Dosage Forms

Tablet

Levorphanolum [Inn-Latin] Indication

For the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate

Levorphanolum [Inn-Latin] Pharmacology

Levorphanol is a potent synthetic opioid analgesic indicated for the management of moderate to severe pain or as a preoperative medication where an opioid analgesic is appropriate. Levorphanol is similar to morphine in its actions, however it is up to 8 times more potent than morphine. Levorphanol produces a degree of respiratory depression similar to that produced by morphine at equianalgesic doses, and like many mu-opioid drugs, levorphanol produces euphoria or has a positive effect on mood in many individuals.

Levorphanolum [Inn-Latin] Absorption

Levorphanol is well absorbed after PO administration with peak plasma concentrations occurring approximately 1 hour after dosing.

Levorphanolum [Inn-Latin] side effects and Toxicity

LD₅₀=150 mg/kg (orally in rats). Signs of overdose include nausea, emesis, dizziness, respiratory depression, hypotension, urinary retention, cardiac arrhythmias, allergic reactions, skin rash, and uticaria.

Levorphanolum [Inn-Latin] Patient Information

No information avaliable

Levorphanolum [Inn-Latin] Organisms Affected

Humans and other mammals