Ethopropazine
Brand names,
Ethopropazine
Analogs
Ethopropazine
Brand Names Mixture
Ethopropazine
Chemical_Formula
C19H24N2S
Ethopropazine
RX_link
No information avaliable
Ethopropazine
fda sheet
Ethopropazine
msds (material safety sheet)
Ethopropazine
Synthesis Reference
No information avaliable
Ethopropazine
Molecular Weight
312.473 g/mol
Ethopropazine
Melting Point
64.5 oC
Ethopropazine
H2O Solubility
0.693 mg/L
Ethopropazine
State
Solid
Ethopropazine
LogP
5.772
Ethopropazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Ethopropazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Ethopropazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Ethopropazine
Absorption
Well-absorbed from the gastrointestinal tract.
Ethopropazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Ethopropazine
Patient Information
Ethopropazine
Organisms Affected
Humans and other mammals