Phenopropazine
Brand names,
Phenopropazine
Analogs
Phenopropazine
Brand Names Mixture
Phenopropazine
Chemical_Formula
C19H24N2S
Phenopropazine
RX_link
No information avaliable
Phenopropazine
fda sheet
Phenopropazine
msds (material safety sheet)
Phenopropazine
Synthesis Reference
No information avaliable
Phenopropazine
Molecular Weight
312.473 g/mol
Phenopropazine
Melting Point
64.5 oC
Phenopropazine
H2O Solubility
0.693 mg/L
Phenopropazine
State
Solid
Phenopropazine
LogP
5.772
Phenopropazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Phenopropazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Phenopropazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Phenopropazine
Absorption
Well-absorbed from the gastrointestinal tract.
Phenopropazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Phenopropazine
Patient Information
Phenopropazine
Organisms Affected
Humans and other mammals