Parphezin
Brand names,
Parphezin
Analogs
Parphezin
Brand Names Mixture
Parphezin
Chemical_Formula
C19H24N2S
Parphezin
RX_link
No information avaliable
Parphezin
fda sheet
Parphezin
msds (material safety sheet)
Parphezin
Synthesis Reference
No information avaliable
Parphezin
Molecular Weight
312.473 g/mol
Parphezin
Melting Point
64.5 oC
Parphezin
H2O Solubility
0.693 mg/L
Parphezin
State
Solid
Parphezin
LogP
5.772
Parphezin
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Parphezin
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Parphezin
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Parphezin
Absorption
Well-absorbed from the gastrointestinal tract.
Parphezin
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Parphezin
Patient Information
Parphezin
Organisms Affected
Humans and other mammals