Prophenaminum
Brand names,
Prophenaminum
Analogs
Prophenaminum
Brand Names Mixture
Prophenaminum
Chemical_Formula
C19H24N2S
Prophenaminum
RX_link
No information avaliable
Prophenaminum
fda sheet
Prophenaminum
msds (material safety sheet)
Prophenaminum
Synthesis Reference
No information avaliable
Prophenaminum
Molecular Weight
312.473 g/mol
Prophenaminum
Melting Point
64.5 oC
Prophenaminum
H2O Solubility
0.693 mg/L
Prophenaminum
State
Solid
Prophenaminum
LogP
5.772
Prophenaminum
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Prophenaminum
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Prophenaminum
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Prophenaminum
Absorption
Well-absorbed from the gastrointestinal tract.
Prophenaminum
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Prophenaminum
Patient Information
Prophenaminum
Organisms Affected
Humans and other mammals