Parfezin
Brand names,
Parfezin
Analogs
Parfezin
Brand Names Mixture
Parfezin
Chemical_Formula
C19H24N2S
Parfezin
RX_link
No information avaliable
Parfezin
fda sheet
Parfezin
msds (material safety sheet)
Parfezin
Synthesis Reference
No information avaliable
Parfezin
Molecular Weight
312.473 g/mol
Parfezin
Melting Point
64.5 oC
Parfezin
H2O Solubility
0.693 mg/L
Parfezin
State
Solid
Parfezin
LogP
5.772
Parfezin
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Parfezin
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Parfezin
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Parfezin
Absorption
Well-absorbed from the gastrointestinal tract.
Parfezin
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Parfezin
Patient Information
Parfezin
Organisms Affected
Humans and other mammals