Isothazine
Brand names,
Isothazine
Analogs
Isothazine
Brand Names Mixture
Isothazine
Chemical_Formula
C19H24N2S
Isothazine
RX_link
No information avaliable
Isothazine
fda sheet
Isothazine
msds (material safety sheet)
Isothazine
Synthesis Reference
No information avaliable
Isothazine
Molecular Weight
312.473 g/mol
Isothazine
Melting Point
64.5 oC
Isothazine
H2O Solubility
0.693 mg/L
Isothazine
State
Solid
Isothazine
LogP
5.772
Isothazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Isothazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Isothazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Isothazine
Absorption
Well-absorbed from the gastrointestinal tract.
Isothazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Isothazine
Patient Information
Isothazine
Organisms Affected
Humans and other mammals