Isothiazine
Brand names,
Isothiazine
Analogs
Isothiazine
Brand Names Mixture
Isothiazine
Chemical_Formula
C19H24N2S
Isothiazine
RX_link
No information avaliable
Isothiazine
fda sheet
Isothiazine
msds (material safety sheet)
Isothiazine
Synthesis Reference
No information avaliable
Isothiazine
Molecular Weight
312.473 g/mol
Isothiazine
Melting Point
64.5 oC
Isothiazine
H2O Solubility
0.693 mg/L
Isothiazine
State
Solid
Isothiazine
LogP
5.772
Isothiazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Isothiazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Isothiazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Isothiazine
Absorption
Well-absorbed from the gastrointestinal tract.
Isothiazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Isothiazine
Patient Information
Isothiazine
Organisms Affected
Humans and other mammals