Profenamine
Brand names,
Profenamine
Analogs
Profenamine
Brand Names Mixture
Profenamine
Chemical_Formula
C19H24N2S
Profenamine
RX_link
No information avaliable
Profenamine
fda sheet
Profenamine
msds (material safety sheet)
Profenamine
Synthesis Reference
No information avaliable
Profenamine
Molecular Weight
312.473 g/mol
Profenamine
Melting Point
64.5 oC
Profenamine
H2O Solubility
0.693 mg/L
Profenamine
State
Solid
Profenamine
LogP
5.772
Profenamine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Profenamine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Profenamine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Profenamine
Absorption
Well-absorbed from the gastrointestinal tract.
Profenamine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Profenamine
Patient Information
Profenamine
Organisms Affected
Humans and other mammals