Aethopropropazin
Brand names,
Aethopropropazin
Analogs
Aethopropropazin
Brand Names Mixture
Aethopropropazin
Chemical_Formula
C19H24N2S
Aethopropropazin
RX_link
No information avaliable
Aethopropropazin
fda sheet
Aethopropropazin
msds (material safety sheet)
Aethopropropazin
Synthesis Reference
No information avaliable
Aethopropropazin
Molecular Weight
312.473 g/mol
Aethopropropazin
Melting Point
64.5 oC
Aethopropropazin
H2O Solubility
0.693 mg/L
Aethopropropazin
State
Solid
Aethopropropazin
LogP
5.772
Aethopropropazin
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Aethopropropazin
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Aethopropropazin
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Aethopropropazin
Absorption
Well-absorbed from the gastrointestinal tract.
Aethopropropazin
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Aethopropropazin
Patient Information
Aethopropropazin
Organisms Affected
Humans and other mammals