Parfezine
Parfezine Brand names, Parfezine Analogs
- Aethopropropazin
- Athapropazine
- Athopropazin
- Dibutil
- Ethapropazine
- Ethopromazine
- Ethopropazine Hydrochloride
- Etopropezina
- Fempropazine
- Fenpropazina
- Isopthazine
- Isotazin
- Isothazine
- Isothazine hydrochloride
- Isothiazine
- Lysivane
- Parcidol
- Pardidol
- Pardisol
- Parfezin
- Parfezine
- Parkin
- Parkisol
- Parphezein
- Parphezin
- Parsidol
- Parsidol hydrochloride
- Parsidol monohydrochloride
- Parsitan
- Parsotil
- Phenopropazine
- Phenoprozine
- Prodictazin
- Prodierazine
- Profenamina
- Profenamina [Inn-Spanish]
- Profenamina [Italian]
- Profenamine
- Profenamine hydrochloride
- Profenamine monohydrochloride
- Profenaminum
- Profenaminum [Inn-Latin]
- Prophenamine
- Prophenaminum
- Rochipel
- Rocipel
- Rodipal
- Tomil
Parfezine Brand Names Mixture
- No information avaliable
Parfezine Chemical_Formula
C19H24N2S
Parfezine RX_link
No information avaliable
Parfezine fda sheet
Parfezine msds (material safety sheet)
Parfezine Synthesis Reference
No information avaliable
Parfezine Molecular Weight
312.473 g/mol
Parfezine Melting Point
64.5 oC
Parfezine H2O Solubility
0.693 mg/L
Parfezine State
Solid
Parfezine LogP
5.772
Parfezine Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Parfezine Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Parfezine Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Parfezine Absorption
Well-absorbed from the gastrointestinal tract.
Parfezine side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Parfezine Patient Information
Parfezine Organisms Affected
Humans and other mammals
