Parkisol
Brand names,
Parkisol
Analogs
Parkisol
Brand Names Mixture
Parkisol
Chemical_Formula
C19H24N2S
Parkisol
RX_link
No information avaliable
Parkisol
fda sheet
Parkisol
msds (material safety sheet)
Parkisol
Synthesis Reference
No information avaliable
Parkisol
Molecular Weight
312.473 g/mol
Parkisol
Melting Point
64.5 oC
Parkisol
H2O Solubility
0.693 mg/L
Parkisol
State
Solid
Parkisol
LogP
5.772
Parkisol
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Parkisol
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Parkisol
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Parkisol
Absorption
Well-absorbed from the gastrointestinal tract.
Parkisol
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Parkisol
Patient Information
Parkisol
Organisms Affected
Humans and other mammals