Isopthazine
Brand names,
Isopthazine
Analogs
Isopthazine
Brand Names Mixture
Isopthazine
Chemical_Formula
C19H24N2S
Isopthazine
RX_link
No information avaliable
Isopthazine
fda sheet
Isopthazine
msds (material safety sheet)
Isopthazine
Synthesis Reference
No information avaliable
Isopthazine
Molecular Weight
312.473 g/mol
Isopthazine
Melting Point
64.5 oC
Isopthazine
H2O Solubility
0.693 mg/L
Isopthazine
State
Solid
Isopthazine
LogP
5.772
Isopthazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Isopthazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Isopthazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Isopthazine
Absorption
Well-absorbed from the gastrointestinal tract.
Isopthazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Isopthazine
Patient Information
Isopthazine
Organisms Affected
Humans and other mammals