Athapropazine
Brand names,
Athapropazine
Analogs
Athapropazine
Brand Names Mixture
Athapropazine
Chemical_Formula
C19H24N2S
Athapropazine
RX_link
No information avaliable
Athapropazine
fda sheet
Athapropazine
msds (material safety sheet)
Athapropazine
Synthesis Reference
No information avaliable
Athapropazine
Molecular Weight
312.473 g/mol
Athapropazine
Melting Point
64.5 oC
Athapropazine
H2O Solubility
0.693 mg/L
Athapropazine
State
Solid
Athapropazine
LogP
5.772
Athapropazine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Athapropazine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Athapropazine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Athapropazine
Absorption
Well-absorbed from the gastrointestinal tract.
Athapropazine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Athapropazine
Patient Information
Athapropazine
Organisms Affected
Humans and other mammals