Parphezein
Brand names,
Parphezein
Analogs
Parphezein
Brand Names Mixture
Parphezein
Chemical_Formula
C19H24N2S
Parphezein
RX_link
No information avaliable
Parphezein
fda sheet
Parphezein
msds (material safety sheet)
Parphezein
Synthesis Reference
No information avaliable
Parphezein
Molecular Weight
312.473 g/mol
Parphezein
Melting Point
64.5 oC
Parphezein
H2O Solubility
0.693 mg/L
Parphezein
State
Solid
Parphezein
LogP
5.772
Parphezein
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Parphezein
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Parphezein
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Parphezein
Absorption
Well-absorbed from the gastrointestinal tract.
Parphezein
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Parphezein
Patient Information
Parphezein
Organisms Affected
Humans and other mammals