Pardidol
Brand names,
Pardidol
Analogs
Pardidol
Brand Names Mixture
Pardidol
Chemical_Formula
C19H24N2S
Pardidol
RX_link
No information avaliable
Pardidol
fda sheet
Pardidol
msds (material safety sheet)
Pardidol
Synthesis Reference
No information avaliable
Pardidol
Molecular Weight
312.473 g/mol
Pardidol
Melting Point
64.5 oC
Pardidol
H2O Solubility
0.693 mg/L
Pardidol
State
Solid
Pardidol
LogP
5.772
Pardidol
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Pardidol
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Pardidol
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Pardidol
Absorption
Well-absorbed from the gastrointestinal tract.
Pardidol
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Pardidol
Patient Information
Pardidol
Organisms Affected
Humans and other mammals