Prophenamine
Brand names,
Prophenamine
Analogs
Prophenamine
Brand Names Mixture
Prophenamine
Chemical_Formula
C19H24N2S
Prophenamine
RX_link
No information avaliable
Prophenamine
fda sheet
Prophenamine
msds (material safety sheet)
Prophenamine
Synthesis Reference
No information avaliable
Prophenamine
Molecular Weight
312.473 g/mol
Prophenamine
Melting Point
64.5 oC
Prophenamine
H2O Solubility
0.693 mg/L
Prophenamine
State
Solid
Prophenamine
LogP
5.772
Prophenamine
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Prophenamine
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Prophenamine
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Prophenamine
Absorption
Well-absorbed from the gastrointestinal tract.
Prophenamine
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Prophenamine
Patient Information
Prophenamine
Organisms Affected
Humans and other mammals