Athopropazin
Brand names,
Athopropazin
Analogs
Athopropazin
Brand Names Mixture
Athopropazin
Chemical_Formula
C19H24N2S
Athopropazin
RX_link
No information avaliable
Athopropazin
fda sheet
Athopropazin
msds (material safety sheet)
Athopropazin
Synthesis Reference
No information avaliable
Athopropazin
Molecular Weight
312.473 g/mol
Athopropazin
Melting Point
64.5 oC
Athopropazin
H2O Solubility
0.693 mg/L
Athopropazin
State
Solid
Athopropazin
LogP
5.772
Athopropazin
Dosage Forms
Tablet (10 mg); Tablet (scored, 50 mg)
Athopropazin
Indication
For use in the treatment of Parkinson's disease and also used to control severe reactions to certain medicines such as reserpine.
Athopropazin
Pharmacology
Ethopropazine, a phenothiazine and antidyskinetic, is used in the treatment of Parkinson's disease. By improving muscle control and reducing stiffness, this drug permits more normal movements of the body as the disease symptoms are reduced. It is also used to control severe reactions to certain medicines such as reserpine, phenothiazines, chlorprothixene, thiothixene, loxapine, and haloperidol. Unlike other NMDA antagonists, ethopropazine — because of its anticholinergic action — is largely devoid of neurotoxic side effects. Ethopropazine also has a slight antihistaminic and local anesthetic effect.
Athopropazin
Absorption
Well-absorbed from the gastrointestinal tract.
Athopropazin
side effects and Toxicity
Symptoms of overdose include severe clumsiness or unsteadiness, severe drowsiness, severe dryness of mouth, nose, or throat, fast heartbeat, shortness of breath or troubled breathing, and warmth, dryness, and flushing of skin.
Athopropazin
Patient Information
Athopropazin
Organisms Affected
Humans and other mammals