Doxycycline
Doxycycline Brand names, Doxycycline Analogs
Doxycycline Brand Names Mixture
- No information avaliable
Doxycycline Chemical_Formula
C22H24N2O8
Doxycycline RX_link
http://www.rxlist.com/cgi/generic/doxycyc.htm
Doxycycline fda sheet
Doxycycline msds (material safety sheet)
Doxycycline Synthesis Reference
C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)
Doxycycline Molecular Weight
444.435 g/mol
Doxycycline Melting Point
201 oC
Doxycycline H2O Solubility
630 mg/L
Doxycycline State
Solid
Doxycycline LogP
-1.219
Doxycycline Dosage Forms
Tablet; Capsule; Gel; Liquid; Powder; Powder for solution
Doxycycline Indication
For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve
Doxycycline Pharmacology
Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.
Doxycycline Absorption
completely absorbed after oral administration
Doxycycline side effects and Toxicity
anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)
Doxycycline Patient Information
Doxycycline Organisms Affected
Enteric bacteria and other eubacteria
