Clindamycin

Clindamycin Brand names, Clindamycin Analogs

Clindamycin Brand Names Mixture

No information avaliable

Clindamycin Chemical_Formula

C₁₈H₃₃ClN₂O₅S

Clindamycin RX_link

http://www.rxlist.com/cgi/generic2/clindam.htm

Clindamycin fda sheet

Clindamycin FDA

Clindamycin msds (material safety sheet)

Clindamycin Synthesis Reference

Birkenmeyer, U.S. Pat. 3,475,407(1970)

Clindamycin Molecular Weight

424.984 g/mol

Clindamycin Melting Point

255 ^oC

Clindamycin H₂O Solubility

30.6 mg/L

Clindamycin State

Solid

Clindamycin LogP

1.224

Clindamycin Dosage Forms

Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules

Clindamycin Indication

For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Clindamycin Pharmacology

Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.

Clindamycin Absorption

- 90% - oral

Clindamycin side effects and Toxicity

Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.

Clindamycin Patient Information

Clindamycin Organisms Affected

Enteric bacteria and other eubacteria