Cleocin Pediatric
Brand names,
Cleocin Pediatric
Analogs
Cleocin Pediatric
Brand Names Mixture
Cleocin Pediatric
Chemical_Formula
C18H33ClN2O5S
Cleocin Pediatric
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Cleocin Pediatric
fda sheet
Cleocin Pediatric
msds (material safety sheet)
Cleocin Pediatric
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Cleocin Pediatric
Molecular Weight
424.984 g/mol
Cleocin Pediatric
Melting Point
255 oC
Cleocin Pediatric
H2O Solubility
30.6 mg/L
Cleocin Pediatric
State
Solid
Cleocin Pediatric
LogP
1.224
Cleocin Pediatric
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Cleocin Pediatric
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Cleocin Pediatric
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Cleocin Pediatric
Absorption
- 90% - oral
Cleocin Pediatric
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Cleocin Pediatric
Patient Information
Cleocin Pediatric
Organisms Affected
Enteric bacteria and other eubacteria