Sobelin
Brand names,
Sobelin
Analogs
Sobelin
Brand Names Mixture
Sobelin
Chemical_Formula
C18H33ClN2O5S
Sobelin
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Sobelin
fda sheet
Sobelin
msds (material safety sheet)
Sobelin
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Sobelin
Molecular Weight
424.984 g/mol
Sobelin
Melting Point
255 oC
Sobelin
H2O Solubility
30.6 mg/L
Sobelin
State
Solid
Sobelin
LogP
1.224
Sobelin
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Sobelin
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Sobelin
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Sobelin
Absorption
- 90% - oral
Sobelin
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Sobelin
Patient Information
Sobelin
Organisms Affected
Enteric bacteria and other eubacteria