Cleocin Hcl
Brand names,
Cleocin Hcl
Analogs
Cleocin Hcl
Brand Names Mixture
Cleocin Hcl
Chemical_Formula
C18H33ClN2O5S
Cleocin Hcl
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Cleocin Hcl
fda sheet
Cleocin Hcl
msds (material safety sheet)
Cleocin Hcl
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Cleocin Hcl
Molecular Weight
424.984 g/mol
Cleocin Hcl
Melting Point
255 oC
Cleocin Hcl
H2O Solubility
30.6 mg/L
Cleocin Hcl
State
Solid
Cleocin Hcl
LogP
1.224
Cleocin Hcl
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Cleocin Hcl
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Cleocin Hcl
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Cleocin Hcl
Absorption
- 90% - oral
Cleocin Hcl
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Cleocin Hcl
Patient Information
Cleocin Hcl
Organisms Affected
Enteric bacteria and other eubacteria