Cleocin

Cleocin Brand names, Cleocin Analogs

Cleocin Brand Names Mixture

No information avaliable

Cleocin Chemical_Formula

C₁₈H₃₃ClN₂O₅S

Cleocin RX_link

http://www.rxlist.com/cgi/generic2/clindam.htm

Cleocin fda sheet

Cleocin FDA

Cleocin msds (material safety sheet)

Cleocin Synthesis Reference

Birkenmeyer, U.S. Pat. 3,475,407(1970)

Cleocin Molecular Weight

424.984 g/mol

Cleocin Melting Point

255 ^oC

Cleocin H₂O Solubility

30.6 mg/L

Cleocin State

Solid

Cleocin LogP

1.224

Cleocin Dosage Forms

Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules

Cleocin Indication

For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Cleocin Pharmacology

Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.

Cleocin Absorption

- 90% - oral

Cleocin side effects and Toxicity

Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.

Cleocin Patient Information

Cleocin Organisms Affected

Enteric bacteria and other eubacteria