Cleocin T
Brand names,
Cleocin T
Analogs
Cleocin T
Brand Names Mixture
Cleocin T
Chemical_Formula
C18H33ClN2O5S
Cleocin T
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Cleocin T
fda sheet
Cleocin T
msds (material safety sheet)
Cleocin T
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Cleocin T
Molecular Weight
424.984 g/mol
Cleocin T
Melting Point
255 oC
Cleocin T
H2O Solubility
30.6 mg/L
Cleocin T
State
Solid
Cleocin T
LogP
1.224
Cleocin T
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Cleocin T
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Cleocin T
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Cleocin T
Absorption
- 90% - oral
Cleocin T
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Cleocin T
Patient Information
Cleocin T
Organisms Affected
Enteric bacteria and other eubacteria