Cleocin T Topical Solution
Brand names,
Cleocin T Topical Solution
Analogs
Cleocin T Topical Solution
Brand Names Mixture
Cleocin T Topical Solution
Chemical_Formula
C18H33ClN2O5S
Cleocin T Topical Solution
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Cleocin T Topical Solution
fda sheet
Cleocin T Topical Solution
msds (material safety sheet)
Cleocin T Topical Solution
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Cleocin T Topical Solution
Molecular Weight
424.984 g/mol
Cleocin T Topical Solution
Melting Point
255 oC
Cleocin T Topical Solution
H2O Solubility
30.6 mg/L
Cleocin T Topical Solution
State
Solid
Cleocin T Topical Solution
LogP
1.224
Cleocin T Topical Solution
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Cleocin T Topical Solution
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Cleocin T Topical Solution
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Cleocin T Topical Solution
Absorption
- 90% - oral
Cleocin T Topical Solution
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Cleocin T Topical Solution
Patient Information
Cleocin T Topical Solution
Organisms Affected
Enteric bacteria and other eubacteria