Clindets

Clindets Brand names, Clindets Analogs

Clindets Brand Names Mixture

No information avaliable

Clindets Chemical_Formula

C₁₈H₃₃ClN₂O₅S

Clindets RX_link

http://www.rxlist.com/cgi/generic2/clindam.htm

Clindets fda sheet

Clindets FDA

Clindets msds (material safety sheet)

Clindets Synthesis Reference

Birkenmeyer, U.S. Pat. 3,475,407(1970)

Clindets Molecular Weight

424.984 g/mol

Clindets Melting Point

255 ^oC

Clindets H₂O Solubility

30.6 mg/L

Clindets State

Solid

Clindets LogP

1.224

Clindets Dosage Forms

Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules

Clindets Indication

For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)

Clindets Pharmacology

Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.

Clindets Absorption

- 90% - oral

Clindets side effects and Toxicity

Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.

Clindets Patient Information

Clindets Organisms Affected

Enteric bacteria and other eubacteria