Clinimycin
Brand names,
Clinimycin
Analogs
Clinimycin
Brand Names Mixture
Clinimycin
Chemical_Formula
C18H33ClN2O5S
Clinimycin
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Clinimycin
fda sheet
Clinimycin
msds (material safety sheet)
Clinimycin
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Clinimycin
Molecular Weight
424.984 g/mol
Clinimycin
Melting Point
255 oC
Clinimycin
H2O Solubility
30.6 mg/L
Clinimycin
State
Solid
Clinimycin
LogP
1.224
Clinimycin
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Clinimycin
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Clinimycin
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Clinimycin
Absorption
- 90% - oral
Clinimycin
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Clinimycin
Patient Information
Clinimycin
Organisms Affected
Enteric bacteria and other eubacteria