Dalacin C Phosphate
Brand names,
Dalacin C Phosphate
Analogs
Dalacin C Phosphate
Brand Names Mixture
Dalacin C Phosphate
Chemical_Formula
C18H33ClN2O5S
Dalacin C Phosphate
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Dalacin C Phosphate
fda sheet
Dalacin C Phosphate
msds (material safety sheet)
Dalacin C Phosphate
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Dalacin C Phosphate
Molecular Weight
424.984 g/mol
Dalacin C Phosphate
Melting Point
255 oC
Dalacin C Phosphate
H2O Solubility
30.6 mg/L
Dalacin C Phosphate
State
Solid
Dalacin C Phosphate
LogP
1.224
Dalacin C Phosphate
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Dalacin C Phosphate
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Dalacin C Phosphate
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Dalacin C Phosphate
Absorption
- 90% - oral
Dalacin C Phosphate
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Dalacin C Phosphate
Patient Information
Dalacin C Phosphate
Organisms Affected
Enteric bacteria and other eubacteria