Chlolincocin
Brand names,
Chlolincocin
Analogs
Chlolincocin
Brand Names Mixture
Chlolincocin
Chemical_Formula
C18H33ClN2O5S
Chlolincocin
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Chlolincocin
fda sheet
Chlolincocin
msds (material safety sheet)
Chlolincocin
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Chlolincocin
Molecular Weight
424.984 g/mol
Chlolincocin
Melting Point
255 oC
Chlolincocin
H2O Solubility
30.6 mg/L
Chlolincocin
State
Solid
Chlolincocin
LogP
1.224
Chlolincocin
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Chlolincocin
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Chlolincocin
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Chlolincocin
Absorption
- 90% - oral
Chlolincocin
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Chlolincocin
Patient Information
Chlolincocin
Organisms Affected
Enteric bacteria and other eubacteria