Clindagel
Brand names,
Clindagel
Analogs
Clindagel
Brand Names Mixture
Clindagel
Chemical_Formula
C18H33ClN2O5S
Clindagel
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Clindagel
fda sheet
Clindagel
msds (material safety sheet)
Clindagel
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Clindagel
Molecular Weight
424.984 g/mol
Clindagel
Melting Point
255 oC
Clindagel
H2O Solubility
30.6 mg/L
Clindagel
State
Solid
Clindagel
LogP
1.224
Clindagel
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Clindagel
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Clindagel
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Clindagel
Absorption
- 90% - oral
Clindagel
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Clindagel
Patient Information
Clindagel
Organisms Affected
Enteric bacteria and other eubacteria