Dalacin
Brand names,
Dalacin
Analogs
Dalacin
Brand Names Mixture
Dalacin
Chemical_Formula
C18H33ClN2O5S
Dalacin
RX_link
http://www.rxlist.com/cgi/generic2/clindam.htm
Dalacin
fda sheet
Dalacin
msds (material safety sheet)
Dalacin
Synthesis Reference
Birkenmeyer, U.S. Pat. 3,475,407(1970)
Dalacin
Molecular Weight
424.984 g/mol
Dalacin
Melting Point
255 oC
Dalacin
H2O Solubility
30.6 mg/L
Dalacin
State
Solid
Dalacin
LogP
1.224
Dalacin
Dosage Forms
Capsules; Intramuscular solution; Intravenousparenteral solution; Topical solution; Topical lotion; Topical gel; Vaginal cream; Vaginal ovules
Dalacin
Indication
For the treatment of serious infections caused by susceptible anaerobic bacteria (anaerobes, streptococci, pneumococci, and staphylococci)
Dalacin
Pharmacology
Clindamycin is an antibiotic, similar to and a derivative of lincomycin. Clindamycin can be used in topical or systemic treatment. It is effective as an anti-anaerobic antibiotic and antiprotozoal.
Dalacin
Absorption
- 90% - oral
Dalacin
side effects and Toxicity
Orally and parenterally administered clindamycin has been associated with severe colitis (pseudomembranous colitis) which may result in patient death. Use of the topical formulation of clindamycin results in absorption of the antibiotic from the skin surface. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical and systemic clindamycin.
Dalacin
Patient Information
Dalacin
Organisms Affected
Enteric bacteria and other eubacteria