Categoria
Isoptin
Marchi,
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Analoghi
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Marchi miscela
Tarka (trandolapril + verapamil hydrochloride)
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Formula chimica
C27H38N2O4
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RX link
http://www.rxlist.com/cgi/generic/verapsr.htm
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FDA foglio
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DMS (foglio di materiale di sicurezza)
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Sintesi di riferimento
Dengel, US Pat. 3,261,859 (1966)
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Peso molecolare
454.602 g/mol
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Temperatura di fusione
< 25 oC
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H2O Solubilita
4,47 mg / L
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Stato
Liquid
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LogP
5.931
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Forme di dosaggio
Capsule (rilascio prolungato); liquidi; soluzione; Tablet; Tablet (a rilascio prolungato)
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Indicazione
Per il trattamento di ipertensione e angina.
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Farmacologia
Verapamil, un agente antiaritmico di classe IV, viene utilizzato come inibitore dei canali del blocco (CCB), agente per il trattamento dell'angina, ipertensione, e per tachiaritmie sopraventricolari.
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Assorbimento
90%
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Tossicita
LD50 = 8 mg / kg (iv nei topi)
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Informazioni paziente
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
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Atto interessato organismi
Gli esseri umani e altri mammiferi