Veracim
Brand names,
Veracim
Analogs
Veracim
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Veracim
Chemical_Formula
C27H38N2O4
Veracim
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Veracim
fda sheet
Veracim
msds (material safety sheet)
Veracim
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Veracim
Molecular Weight
454.602 g/mol
Veracim
Melting Point
< 25 oC
Veracim
H2O Solubility
4.47 mg/L
Veracim
State
Liquid
Veracim
LogP
5.931
Veracim
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Veracim
Indication
For the treatment of hypertension and angina.
Veracim
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Veracim
Absorption
90%
Veracim
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Veracim
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Veracim
Organisms Affected
Humans and other mammals