Vasolan
Brand names,
Vasolan
Analogs
Vasolan
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Vasolan
Chemical_Formula
C27H38N2O4
Vasolan
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Vasolan
fda sheet
Vasolan
msds (material safety sheet)
Vasolan
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Vasolan
Molecular Weight
454.602 g/mol
Vasolan
Melting Point
< 25 oC
Vasolan
H2O Solubility
4.47 mg/L
Vasolan
State
Liquid
Vasolan
LogP
5.931
Vasolan
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Vasolan
Indication
For the treatment of hypertension and angina.
Vasolan
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Vasolan
Absorption
90%
Vasolan
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Vasolan
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Vasolan
Organisms Affected
Humans and other mammals