Cardibeltin
Brand names,
Cardibeltin
Analogs
Cardibeltin
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Cardibeltin
Chemical_Formula
C27H38N2O4
Cardibeltin
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Cardibeltin
fda sheet
Cardibeltin
msds (material safety sheet)
Cardibeltin
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Cardibeltin
Molecular Weight
454.602 g/mol
Cardibeltin
Melting Point
< 25 oC
Cardibeltin
H2O Solubility
4.47 mg/L
Cardibeltin
State
Liquid
Cardibeltin
LogP
5.931
Cardibeltin
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Cardibeltin
Indication
For the treatment of hypertension and angina.
Cardibeltin
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Cardibeltin
Absorption
90%
Cardibeltin
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Cardibeltin
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Cardibeltin
Organisms Affected
Humans and other mammals