Verelan
Brand names,
Verelan
Analogs
Verelan
Brand Names Mixture
- Tarka (trandolapril + verapamil hydrochloride)
Verelan
Chemical_Formula
C27H38N2O4
Verelan
RX_link
http://www.rxlist.com/cgi/generic/verapsr.htm
Verelan
fda sheet
Verelan
msds (material safety sheet)
Verelan
Synthesis Reference
Dengel, U.S. Pat. 3,261,859 (1966)
Verelan
Molecular Weight
454.602 g/mol
Verelan
Melting Point
< 25 oC
Verelan
H2O Solubility
4.47 mg/L
Verelan
State
Liquid
Verelan
LogP
5.931
Verelan
Dosage Forms
Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)
Verelan
Indication
For the treatment of hypertension and angina.
Verelan
Pharmacology
Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.
Verelan
Absorption
90%
Verelan
side effects and Toxicity
LD50=8 mg/kg (i.v. in mice)
Verelan
Patient Information
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Verelan
Organisms Affected
Humans and other mammals