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Calan Brand names, Calan Analogs

Calan Brand Names Mixture

  • Tarka (trandolapril + verapamil hydrochloride)

Calan Chemical_Formula


Calan RX_link

Calan fda sheet

Calan FDA

Calan msds (material safety sheet)

Calan Synthesis Reference

Dengel, U.S. Pat. 3,261,859 (1966)

Calan Molecular Weight

454.602 g/mol

Calan Melting Point

< 25 oC

Calan H2O Solubility

4.47 mg/L

Calan State


Calan LogP


Calan Dosage Forms

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

Calan Indication

For the treatment of hypertension and angina.

Calan Pharmacology

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

Calan Absorption


Calan side effects and Toxicity

LD50=8 mg/kg (i.v. in mice)

Calan Patient Information

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Calan Organisms Affected

Humans and other mammals