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Isoptimo Brand names, Isoptimo Analogs

Isoptimo Brand Names Mixture

  • Tarka (trandolapril + verapamil hydrochloride)

Isoptimo Chemical_Formula


Isoptimo RX_link

Isoptimo fda sheet

Isoptimo FDA

Isoptimo msds (material safety sheet)

Isoptimo Synthesis Reference

Dengel, U.S. Pat. 3,261,859 (1966)

Isoptimo Molecular Weight

454.602 g/mol

Isoptimo Melting Point

< 25 oC

Isoptimo H2O Solubility

4.47 mg/L

Isoptimo State


Isoptimo LogP


Isoptimo Dosage Forms

Capsule (sustained-release); Liquid; Solution; Tablet; Tablet (extended-release)

Isoptimo Indication

For the treatment of hypertension and angina.

Isoptimo Pharmacology

Verapamil, a class IV antiarrhythmic agent, is used as a calcium-channel blocking (CCB) agent for the treatment of angina, hypertension, and for supraventricular tachyarrhythmias.

Isoptimo Absorption


Isoptimo side effects and Toxicity

LD50=8 mg/kg (i.v. in mice)

Isoptimo Patient Information

Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses may need some adjustment, make sure to have your condition monitored regularly.

Isoptimo Organisms Affected

Humans and other mammals